RNA Details
Disease Name
neurofibromatosis
Tissue
brain
RNA Symbol
CDKN2B-AS1
RNA ID
100048912
RNA Type
lncrna
Alteration Pattern
up regulation
Species
homo sapiens
Detection Methods
q-PCR; microarray
Target
NA
Pathway
NA
PubMed ID
22034633
Title
Role of noncoding RNA ANRIL in genesis of plexiform neurofibromas in neurofibromatosis type 1
Year
2011
Function
"Single-nucleotide polymorphism rs2151280 (located in ANRIL) was statistically significantly associated with the number of PNFs in NF1 patients. In addition,allele T of rs2151280 was statistically significantly associated with reduced ANRIL transcript levels,suggesting that modulation of ANRIL expression mediates PNF susceptibility."